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Human Renal Glomerular Epithelial Cells: HRGEpC




Human Renal Glomerular Epithelial Cells: HRGEpC

Human Renal Glomerular Epithelial Cells (HRGEpC) have received increasing attention lately as researchers work to better understand their pathophysiology.  Active investigations suggest HRGEpC may serve as a selective permeability barrier to urinary filtrate.  Other studies indicate functions related to mechanosensing and contraction.
As a network of capillaries at the beginning of the kidney nephron, the glomerulus filters blood carried out by the nephron during urine formation. The blood plasma is filtered by passing through the glomerular membrane, consisting of the capillary wall and the epithelial layer of Bowman's capsule. This glomerular capillary tuft is supported by a matrix of collagen and surrounded by an envelope of epithelial cells.
While the precise role of HRGEpC in disease remains unclear, glomerular problems are a leading cause of kidney disease.  When activated, HRGEpC show elevated proliferation, migration and ECM production, activities possibly tied to glomerulonephritis, diabetic nephropathy and other pathologies.
HRGEpC are rigorously tested for their ability to attach and spread on tissue culture ware and proliferate in RenaEpi Growth Medium.
Characterization: HRGEpC stain positive for Nephrin, pan-CK and Vimentin expression by ICC staining

Параметры



Human Renal Glomerular Epithelial Cells: HRGEpC

TissueNormal healthy human kidney
QCNo bacteria, yeast, fungi, mycoplasma, virus
CharacterNephrin, pan-CK, Vimentin positive
BioassayAttach, spread, proliferate in Growth Med
Cryovial500,000 HRGEpC (2nd passage) frozen in Basal Med w/ 10% FBS, 10% DMSO
KitCryovial frozen HRGEpC (938-05n), Gr Med (911-500), Subculture Rgnt Kit (090K)
ProliferatingShipped in Gr Med, 3rd psg (flasks or plates)
Doublings2-3


Документы



Human Renal Glomerular Epithelial Cells: HRGEpC



НазваниеКодЦена
5x10^5 Cells (Neonatal), Medium & Subculture Reagents (See Details tab for specifics) 938K-05n 97944.06 руб.



НазваниеКодЦена
Frozen HRGEpC (5x10^5) 938-05n 78695.01 руб.



НазваниеКодЦена
Actively growing, dividing cells in medium 938-96Wn 117759.17 руб.
Actively growing, dividing cells in medium 938-25n 78695.01 руб.
Actively growing, dividing cells in medium 938-6Wn 102473.14 руб.
Actively growing, dividing cells in medium 938-75n 102473.14 руб.



Extended Family Products

НазваниеКодЦена
For general cryopreservation of most primary cells. Contains FBS & DMSO. 040-50 5944.53 руб.



НазваниеКодЦена
100 tests 028-S 3963.02 руб.
500 tests 028-01 15337.25 руб.



НазваниеКодЦена
124 x 24-Well Rxns TF102K 44583.98 руб.
25 x 24-Well Rxns TF102KS 5938.7 руб.



НазваниеКодЦена
Total RNA prepared from human kidney tissue 1H50-50 15307.43 руб.
Total RNA prepared from human kidney tissue 1H50-250 57662.21 руб.



НазваниеКодЦена
100 ml each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution 090K 6063.19 руб.



Related Products

НазваниеКодЦена
Basal medium (contains no growth supplement). Add GS before use. 910-500 7133.7 руб.



НазваниеКодЦена
All-in-one ready-to-use 911-500 13672.81 руб.



НазваниеКодЦена
Basal medium & growth supplement sold together packaged separately 911K-500 14861.33 руб.



НазваниеКодЦена
Added to Basal Medium to create Growth Medium 911-GS 7727.63 руб.




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