1. Каталог >
  2. Cell Applications >
  3. Клеточные линии >
  4. По типам клеток (клеточные линии) >
  5. Эндотелий: клетки >

Клетки эндотелия коронарной артерии человека: HCAEC. Первичные клеточные линии Cell Applications.

Human Coronary Artery Endothelial Cells: HCAEC

Клетки Эндотелия Коронарной Артерии (HCAEC) от Cell Applications, Inc. предоставляют прекрасную модельную систему для изучения всех аспектов сердечно-сосудистых функций и заболеваний, и они использовались в десятках исследовательских публикаций, например:

(Текст на языке оригинала)
  • Understand the mechanism of the anti-inflammatory properties of HDL, and demonstrate for the first time that mature miRNA can control gene expression in a cell where it is neither transcribed nor processed
  • Study mechanisms of angiogenesis, as well as oxidative stress and inflammation related pathways in endothelia, including gender and race specific differences in patients with peripheral artery disease
  • Elucidate molecular mechanisms of various cardiovascular risk factors, including those associated with diabetes
  • Understand the mode of action and cardiovascular protection effects of various natural compounds, vitamins and drug candidates
  • Develop and evaluate scaffolds and hydrogels for cardiac tissue engineering, and new treatment strategies to prevent stent restenosis
  • Compare effects of BMP-4 on HCAEC and Human Pulmonary Artery Endothelial Cells (HPAEC, also от Cell Applications, Inc.)
  • Show that only in HCAEC BMP-4 treatment induced ROS, activated NF-kB, ICAM-1 and increased monocyte adhesiveness, explaining why its upregulation leads to atherosclerosis and hypertension in the systemic, but not pulmonary circulation

Кроме того, HCAEC, вместе с клетками эндотелия аорты(HAOEC), подключичной(HScAEC), сонной (HCtAEC) и брахиоцефальной (HBcAEC) артерий от Cell Applications, Inc., использовались для демонстрации того, что не только кровеносные сосуды из различных тканей весьма различны, они также по-разному взаимодействуют с лейкоцитами при воспалительном ответе (Scott, 2013). Авторы далее показали, что дифференциальное N-гликозилирование обычно экспрессируемых молекул сосудистой адгезии может отвечать за это различие, как и за молудирование сигналов при покоящихся и активированных условиях воспаления. Это также объясняет, почему специфические сосудистые русла могут быть более или менее восприимчевы к отдельным заболеваниями или стимулам. Важно, что при использовании клеток из различных источников эти результаты не могли бы быть убедительно подтверждены из-за ряда неконтролируемых факторов – таких, как возраст, раса, генетическая вариабельность или образ жизни доноров. Для устранения вариабельности от донора к донору, исследователи воспользовались преимуществами огромного ассортимента  Cell Applications, включая возможность заказать набор эндотелиальных клеток, полученных в разных сосудистых руслах одного донора.

Из-за сложной неоднородности, существующей не только между разными донорами, но также между различными сосудистыми руслами одной особе, представляется целесообразным подтвердить новые данные на партиях первичных клеток, полученных с нескольких разных источников.

НазваниеКодЦена
HCAEC Total Kit: Media, Subculture Reagents & Cells, Adult 300K-05a 98680 руб. 1 Kit
HCAEC Total Kit: Media, Subculture Reagents & Cells, Plaque, Adult 300qK-05a 110569.06 руб. 1 Kit



НазваниеКодЦена
Cryopreserved HCAEC 300-05a 81440.34 руб. 1 Ampoule
Cryopreserved HCAEC, Plaque 300q-05a 93329.4 руб. 1 Ampoule



НазваниеКодЦена
Cryopreserved HCAEC from donor with Type 2 Diabetes 300T2D-05a 85488.3 руб. 1 Ampoule



НазваниеКодЦена
HCAEC-T2D Total Kit: Media, Subculture Reagents & Cells, from donor with Type 2 Diabetes, Adult 300T2DK-05a 102585.96 руб. 1 Kit



НазваниеКодЦена
Proliferating HCAEC 301-25a 82629.5 руб. T-25 Flask
Proliferating HCAEC 301-75a 105219.11 руб. T-75 Flask
Proliferating HCAEC 301-6Wa 103078.74 руб. 6 well
Proliferating HCAEC 301-96Wa 117345.49 руб. 96 well







Extended Family Products

НазваниеКодЦена
For general cryopreservation of most primary cells. Contains FBS & DMSO. 040-50 5944.53 руб. 50 ml



НазваниеКодЦена
100 tests 028-S 3963.02 руб. Sample
500 tests 028-01 15337.25 руб. 1 bottle



НазваниеКодЦена
25 x 24-Well Rxns TF101KS 5938.7 руб. 1 Sample Kit
250 x 24-Well Rxns TF101K 47556.25 руб. 1 Kit



НазваниеКодЦена
Total RNA prepared from Human Coronary Artery Endothelial Cells, adult 300-R10a 45178.57 руб. 10 ug
Total RNA prepared from Human Coronary Artery Endothelial Cells, adult 300-R25a 90357.13 руб. 25 ug



НазваниеКодЦена
Total RNA prepared from human heart tissue 1H30-50 15307.43 руб. 50 ug
Total RNA prepared from human heart tissue 1H30-250 57662.21 руб. 250 ug



НазваниеКодЦена
100 ml each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution 090K 6063.19 руб. 100 ml



Related Products

НазваниеКодЦена
All-in-one ready-to-use 212-500 13078.23 руб. 500 ml
Growth medium without antibiotics 212A-500 13672.81 руб. 500 ml
Growth medium without phenol red 212PR-500 13078.23 руб. 500 ml



НазваниеКодЦена
Basal medium & growth supplement sold together packaged separately 212K-500 13078.23 руб. Yields 500ml
Growth medium kit without phenol red 212KPR-500 14386.05 руб. yields 500 ml



НазваниеКодЦена
Added to Basal Medium to create Growth Medium 212-GS 6895.73 руб. 30 ml



Параметры

Tissue:
Human normal coronary artery. Each lot is tested negative for mycoplasma, bacteria, and fungi.
Cryopreserved ampoule:
2nd passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO.
Kit contains:
Ampuole of cryopreserved HCAEC (300-05a), 500 ml of MesoEndo Endothelial Cell Media (212-500), and a Subculture Reagent Kit (090K).
Proliferating Cells:
Shipped in Growth Medium at 3rd passage in either flasks or multiwell dishes.
Population doublings:
Can be cultured at least 15 doublings

Документы

Публикации

2016
Liu, W., B. Liu, S. Liu, J. Zhang and S. Lin. 2016. Sphingosine-1-phosphate receptor 2 mediates endothelial cells dysfunction by PI3K-Akt pathway under high glucose condition. Eur J Pharmacol, doi:10.1016/j.ejphar.2016.02.056.
2015
Boire, T., M. Gupta, A. Zachman, S. Lee, D. Balikov, K. Kim, L. Bellan, and H. Sung. 2015. Pendant Allyl Crosslinking as a Tunable Shape Memory Actuator for Vascular Applications. Acta Biomaterialia, doi:10.1016/j.actbio.2015.06.004.
Gardner, A., D. Parker, P. Montgomery, D. Sosnowska, A. Casanegra, Z. Ungvari, A. Csiszar, S. Zhang, J. Wang and W. Sonntag. 2015. Influence of diabetes on ambulation and inflammation in men and women with symptomatic peripheral artery disease. J Clin & Translational Endocrinol, 2:137-143.
Sung, H., L. Hofmeister, M. Gupta, S. Crowder, S. Yu, A. Zachman, and D. Jung. 2015. Copolymers and methods of use thereof.  Patent US9012596B2.
Zhong, Y., C. Cheng, Y. Luo, C. Tian, H. Yang, B. Liu, M. Chen, Y. Chen, and S. Liu. 2015. C-reactive protein stimulates RAGE expression in human coronary artery endothelial cells in vitro via ROS generation and ERK/NF-κB activation. Acta Pharmacologica Sinica, 36:440-447.
2014
Dela Paz, N., B. Melchior, F. Shayo, and J. Frangos. 2014. Heparan Sulfates Mediate the Interaction Between PECAM-1 and the Gαq/11 Subunits of Heterotrimeric G Proteins. JBC, 289:7413-7424.
Gardner, A.W., D.E. Parker, P.S. Montgomery, D. Sosnowska, A.I. Casanegra, Z. Ungvari, A. Csiszar, and W.E. Sonntag. 2014. Gender and racial differences in endothelial oxidative stress and inflammation in patients with symptomatic peripheral artery disease. Journal of Vascular Surgery: 10.1016/j.jvs.2014.02.045.
Jihan, T., K. Jair, S.R. Aldwin, K.W. Paul, and J.D. Michael. 2014. The smoking-associated oxidant hypothiocyanous acid induces endothelial nitric oxide synthase dysfunction. Biochemical Journal. 457:89-97.
Johnson, T.D., J.A. DeQuach, R. Gaetani, J. Ungerleider, D. Elhag, V. Nigam, A. Behfar, and K.L. Christman. 2014. Human versus porcine tissue sourcing for an injectable myocardial matrix hydrogel. Biomaterials Science:DOI: 10.1039/C1033BM60283D
Liu, S.-J., Y. Zhong, X.-Y. You, W.-H. Liu, A.-Q. Li, and S.-M. Liu. 2014. Insulin-like growth factor 1 opposes the effects of C-reactive protein on endothelial cell activation. Molecular and cellular biochemistry: 385:199-205
Morgan, P.E., P.J. Sheahan, and M.J. Davies. 2014. Perturbation of Human Coronary Artery Endothelial Cell Redox State and NADPH Generation by Methylglyoxal. PloS one. 9:e86564.
Tabet, F., K.C. Vickers, L.F. Cuesta Torres, C.B. Wiese, B.M. Shoucri, G. Lambert, C. Catherinet, L. Prado-Lourenco, M.G. Levin, S. Thacker, P. Sethupathy, P.J. Barter, A.T. Remaley, and K.-A. Rye. 2014. HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells. Nat Commun. 5:10.1038/ncomms4292.
Torella, D., G.M. Ellison, M. Torella, C. Vicinanza, I. Aquila, C. Iaconetti, M. Scalise, F. Marino, B.J. Henning, F.C. Lewis, C. Gareri, N. Lascar, G. Cuda, T. Salvatore, G. Nappi, C. Indolfi, R. Torella, D. Cozzolino, and F.C. Sasso. 2014. Carbonic Anhydrase Activation Is Associated With Worsened Pathological Remodeling in Human Ischemic Diabetic Cardiomyopathy. Journal of the American Heart Association. 3:10.1161/jaha.1113.000434.
2013
Baotic, I., Z.D. Ge, F. Sedlic, A. Coon, D. Weihrauch, D.C. Warltier, and J.R. Kersten. 2013. Apolipoprotein A-1 mimetic D-4F enhances isoflurane-induced eNOS signaling and cardioprotection during acute hyperglycemia. Am J Phys Heart Circ. 305:H219-227.
Candelario, J., and M. Chachisvilis. 2013. Activity of Bradykinin B2 Receptor Is Regulated by Long-Chain Polyunsaturated Fatty Acids. PloS one. 8:e68151.
Castanares-Zapatero, D., C. Bouleti, C. Sommereyns, B. Gerber, C. Lecut, T. Mathivet, M. Horckmans, D. Communi, M. Foretz, J.L. Vanoverschelde, S. Germain, L. Bertrand, P.F. Laterre, C. Oury, B. Viollet, S. Horman, and C. Beauloye. 2013. Connection between cardiac Vascular Permeability, Myocardial Edema, and Inflammation during Sepsis: Role of the alpha1AMP-Activated Protein Kinase Isoform. Crit Care Med. 10.1097/CCM.0b013e31829866dc
Cho, Y.-E., A. Basu, A. Dai, M. Heldak, and A. Makino. 2013. Coronary endothelial dysfunction and mitochondrial reactive oxygen species in type 2 diabetic mice. Am J Physiol Cell Physiol. 305:C1033-1040.
Csiszar, A., D. Sosnowska, Z. Tucsek, T. Gautam, P. Toth, G. Losonczy, R.J. Colman, R. Weindruch, R.M. Anderson, W.E. Sonntag, and Z. Ungvari. 2013. Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells. The journals of gerontology. Series A. 68:235-249.
dela Paz, N.G., B. Melchior, and J.A. Frangos. 2013. Early VEGFR2 activation in response to flow is VEGF-dependent and mediated by MMP activity. Biochemical and biophysical research communications. 434:641-646.
Dunn, L.L., P.J. Simpson, H.G. Prosser, L. Lecce, G.S. Yuen, A. Buckle, D.P. Sieveking, L.Z. Vanags, P.R. Lim, R.W. Chow, Y.T. Lam, Z. Clayton, S. Bao, M.J. Davies, N. Stadler, D.S. Celermajer, R. Stocker, C.A. Bursill, J.P. Cooke, and M.K. Ng. 2013. A Critical Role for Thioredoxin Interacting Protein in Diabetes-Related Impairment of Angiogenesis. Diabetes:doi: 10.2337/db2313-0417
Eppihimer, M.J., N. Sushkova, J.L. Grimsby, N. Efimova, W. Kai, S. Larson, B. Forsyth, B.A. Huibregtse, K.D. Dawkins, and G.J. Wilson. 2013. Impact of Stent Surface on Thrombogenicity and Vascular Healing A Comparative Analysis of Metallic and Polymeric Surfaces. Circulation: Cardiovascular Interventions. 6:370-377.
Gardner, A.W., D.E. Parker, P.S. Montgomery, D. Sosnowska, A.I. Casanegra, O.L. Esponda, Z. Ungvari, A. Csiszar, and W.E. Sonntag. 2013. Impaired Vascular Endothelial Growth Factor A and Inflammation in Patients with Peripheral Artery Disease. Angiology: 0003319713501376.
Hankins, J.L., K.E. Ward, S.S. Linton, B.M. Barth, R.V. Stahelin, T.E. Fox, and M. Kester. 2013. Ceramide-1-phosphate mediates endothelial cell invasion via the annexin a2/p11 heterotetrameric protein complex. J. Biol. Chemistry. 288:19726-19738.
Hiob, M.A., S.G. Wise, A. Kondyurin, A. Waterhouse, M.M. Bilek, M.K.C. Ng, and A.S. Weiss. 2013. The use of plasma-activated covalent attachment of early domains of tropoelastin to enhance vascular compatibility of surfaces. Biomaterials. 34:7584-7591.
Lee, C.-M., J.-A. Gu, T.-G. Rau, C.-H. Yang, W.-C. Yang, S.-H. Huang, F.-Y. Lin, C.-M. Lin, and S.-T. Huang. 2013. Low-Cytotoxic Synthetic Bromorutaecarpine Exhibits Anti-Inflammation and Activation of Transient Receptor Potential Vanilloid Type 1 Activities. BioMed Research International. 2013: Article ID 795095.
Leucker, T.M., Z.-D. Ge, J. Procknow, Y. Liu, Y. Shi, M. Bienengraeber, D.C. Warltier, and J.R. Kersten. 2013. Impairment of Endothelial-Myocardial Interaction Increases the Susceptibility of Cardiomyocytes to Ischemia/Reperfusion Injury. PloS one. 8:e70088.
Lin, L.Y., I.J. Liu, H.C. Chuang, H.Y. Lin, and K.J. Chuang. 2013. Size and composition effects of household particles on inflammation and endothelial dysfunction of human coronary artery endothelial cells. Atmospheric Environment. 77:490-495.
Liu, S.-J., W.-H. Liu, Y. Zhong, and S.-M. Liu. 2013. Glycogen synthase kinase-3β is involved in C-reactive protein-induced endothelial cell activation. Biochemistry (Moscow). 78:915-919.
Lloyd, M.M., M.A. Grima, B.S. Rayner, K.A. Hadfield, M.J. Davies, and C.L. Hawkins. 2013. Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells. Free Radical Biology and Medicine. 65:1352-1362.
Lord, M.S., M. Jung, B. Cheng, and J.M. Whitelock. 2013. Transcriptional complexity of the HSPG2 gene in the human mast cell line, HMC-1. Matrix Biology. 35:123-31
Lord, M.S., B. Tsoi, C. Gunawan, W.Y. Teoh, R. Amal, and J.M. Whitelock. 2013. Anti-angiogenic activity of heparin functionalised cerium oxide nanoparticles. Biomaterials. 34:8808-8818.
Nsimba, M.M., C. Yamamoto, J.N. Lami, Y. Hayakawa, and T. Kaji. 2013. Effect of a Congolese herbal medicine used in sickle cell anemia on the expression of plasminogen activators in human coronary aortic endothelial cells culture. Journal of ethnopharmacology. 146:594-599.
Scott, D.W., M.O. Vallejo, and R.P. Patel. 2013. Heterogenic endothelial responses to inflammation: role for differential N-glycosylation and vascular bed of origin. Journal of the American Heart Association. 2:e000263-e000263.
Takai, J., A. Santu, H. Zheng, S.D. Koh, M. Ohta, L.M. Filimban, V. Lemaître, R. Teraoka, H. Jo, and H. Miura. 2013. Laminar shear stress upregulates endothelial Ca2+-activated K+ channels KCa2.3 and KCa3.1 via a Ca2+/calmodulin-dependent protein kinase kinase/Akt/p300 cascade. American J. of Physiology -Heart and Circulatory Physiology. 305:H484-H493.
Tan, J.T.M., H.C.G. Prosser, L.Z. Vanags, S.A. Monger, M.K.C. Ng, and C.A. Bursill. 2013. High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1α. The FASEB Journal. article fj.13-233874.
2012
Archacki, S.R., G. Angheloiu, C.S. Moravec, H. Liu, E.J. Topol, and Q.K. Wang. 2012. Comparative gene expression analysis between coronary arteries and internal mammary arteries identifies a role for the TES gene in endothelial cell functions relevant to coronary artery disease. Human molecular genetics. 21:1364-1373.
Bailey-Downs, L.C., M. Mitschelen, D. Sosnowska, P. Toth, J.T. Pinto, P. Ballabh, M.N. Valcarcel-Ares, J. Farley, A. Koller, J.C. Henthorn, C. Bass, W.E. Sonntag, Z. Ungvari, and A. Csiszar. 2012. Liver-Specific Knockdown of IGF-1 Decreases Vascular Oxidative Stress Resistance by Impairing the Nrf2-Dependent Antioxidant Response: A Novel Model of Vascular Aging. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 67A:313-329.
Crowder, S.W., M.K. Gupta, L.H. Hofmeister, A.L. Zachman, and H.-J. Sung. 2012. Modular polymer design to regulate phenotype and oxidative response of human coronary artery cells for potential stent coating applications. Acta Biomaterialia. 8:559-569.DeQuach, J. 2012. Decellularized biomaterials for cell culture and repair after ischemic injury. PhD Dissertation, UC San Diego.
Hankins, J. 2012. Re-branding ceramide-1-phosphate: Not just a ceramide metabolite. PhD Dissertation, Penn State U.
Jemy, J. 2012. Does Human Leukocyte Antigen-G (HLA-G) Play a Role in Immunte Modulation and Vasculopathy in Heart Transplantation?  Masters Thesis, U Toronto.
Kapur, N.K., C. Shenoy, A.A. Yunis, N.N. Mohammad, S. Wilson, V. Paruchuri, E.E. Mackey, X. Qiao, A. Shah, M.L. Esposito, R.H. Karas, and I.Z. Jaffe. 2012. Distinct Effects of Unfractionated Heparin versus Bivalirudin on Circulating Angiogenic Peptides. PloS one. 7:e34344.
Lin, L.-Y., H.-Y. Lin, H.-W. Chen, T.-L. Su, L.-C. Huang, and K.-J. Chuang. 2012. Effects of temple particles on inflammation and endothelial cell response. Science of The Total Environment. 414:68-72.
Melchior, B., and J.A. Frangos. 2012. Gαq/11-mediated intracellular calcium responses to retrograde flow in endothelial cells. American Journal of Physiology-Cell Physiology. 303:C467-C473.
Ramirez-Sanchez, I., H. Aguilar, G. Ceballos, and F. Villarreal. 2012. (-)-Epicatechin-induced calcium independent eNOS activation: roles of HSP90 and AKT. Molecular and cellular biochemistry. 370:141-150.
Riegel, A. 2012. Pro-inflammatory role of P2Y6 receptor signalling during vascular inflammation. PhD Dissertation, Eberhard Karls Universitat Tubingen.
Tso, C., K.-A. Rye, and P. Barter. 2012. Phenotypic and Functional Changes in Blood Monocytes Following Adherence to Endothelium. PloS one. 7:e37091.
Valcarcel-Ares, M., T. Gautam, J. Warrington, L. Bailey-Down, D. Sosnowska, R. de Cabo, G. Losonczy, W. Sonntag, Z. Ungvari, and A. Csiszar. 2012. Disruption of Nrf2 Signaling Impairs Angiogenic Capacity of Endothelial Cells: Implications for Microvascular Aging. J Gerontol A Biol Sci Med Sci, 67:821-829.
Wu, B.J., K. Chen, P.J. Barter, and K.-A. Rye. 2012. Niacin Inhibits Vascular Inflammation via the Induction of Heme Oxygenase-1. Circulation. 125:150-158.
2011
Aoki, T., M. Nishimura, T. Matsuoka, K. Yamamoto, T. Furuyashiki, H. Kataoka, S. Kitaoka, R. Ishibashi, A. Ishibazawa, and S. Miyamoto. 2011. PGE2EP2 signalling in endothelium is activated by haemodynamic stress and induces cerebral aneurysm through an amplifying loop via NFκB. British journal of pharmacology. 163:1237-1249.
Archacki, S. 2011. MOLECULAR IDENTIFICATION OF NOVEL GENES ASSOCIATED WITH ATHEROSCLEROSIS. PhD Dissertation, Cleveland State University.
Bowden, J.A., C.J. Albert, O.S. Barnaby, and D.A. Ford. 2011. Analysis of cholesteryl esters and diacylglycerols using lithiated adducts and electrospray ionization-tandem mass spectrometry. Analytical biochemistry. 417:202-210.
Crowder, S.W. 2011. Modular Design of Stent Polymers Regulates Human Coronary Artery Cell Type-Specific Oxidative Response and Phenotype. Vanderbilt University, MSc dissertation.
Di Bartolo, B., L. Vanags, J. Tan, S. Bao, K.-A. Rye, P. Barter, and C. Bursill. 2011. The apolipoprotein A-I mimetic peptide, ETC-642, reduces chronic vascular inflammation in the rabbit. Lipids in health and disease. 10:224.
Kapur, N.K., K.S. Heffernan, A.A. Yunis, T.A. Nguyen, M.J. Aronovitz, P. Parpos, S. Wilson, C.K. Baker, M.L. Esposito, A. Shah, C.D. Kimmelstiel, A. Weintraub, R.H. Karas, and M.E. Mendelsohn. 2011. Elevated Soluble fms-Like Tyrosine Kinase-1 Levels in Acute Coronary Occlusion. Arteriosclerosis, Thrombosis, and Vascular Biology. 31:443-450.
Quinn, K.L., M. Henriques, A. Tabuchi, B. Han, H. Yang, W.-E. Cheng, S. Tole, H. Yu, A. Luo, E. Charbonney, E. Tullis, A. Lazarus, L.A. Robinson, H. Ni, B.R. Peterson, W.M. Kuebler, A.S. Slutsky, and H. Zhang. 2011. Human Neutrophil Peptides Mediate Endothelial-Monocyte Interaction, Foam Cell Formation, and Platelet Activation. Arter., Thromb., & Vasc. Biol. 31:2070-2079.
Singelyn, J.M., and K.L. Christman. 2011. Modulation of material properties of a decellularized myocardial matrix scaffold. Macromolecular bioscience. 11:731-738.
Vladic, N., Z.-D. Ge, T. Leucker, A.K. Brzezinska, J.-H. Du, Y. Shi, D.C. Warltier, P.F. Pratt, and J.R. Kersten. 2011. Decreased tetrahydrobiopterin and disrupted association of Hsp90 with eNOS by hyperglycemia impair myocardial ischemic preconditioning. American Journal of Physiology - Heart and Circulatory Physiology. 301:H2130-H2139.
Wang, M.-Y., S.-R. Ji, C.-J. Bai, D. El Kebir, H.-Y. Li, J.-M. Shi, W. Zhu, S. Costantino, H.-H. Zhou, L.A. Potempa, J. Zhao, J.G. Filep, and Y. Wu. 2011. A redox switch in C-reactive protein modulates activation of endothelial cells. The FASEB Journal. 25:3186-3196.
2010
Bursill, C., M. Castro, D. Beattie, S. Nakhla, E. van der Vorst, A. Heather, P. Barter, and K. Rye. 2010. High-Density Lipoproteins Suppress Chemokines and Chemokine Receptors In Vitro and In Vivo. Arterioscler Thromb Vasc Biol, 30:1773-1778.
Hung, C.-H., D. Wu, F.-Y. Lin, R.-Y. Yuan, and C.-J. Hu. 2010. Toll-like Receptor 4 and Vascular Cell Adhesion Molecule 1 in Monocyte-Endothelium Adhesion Induced by Lipopolysaccharide. J. Experimental & Clinical Medicine. 2:297-301.
O'Brien, B.J., J.S. Stinson, S.R. Larsen, M.J. Eppihimer, and W.M. Carroll. 2010. A platinum–chromium steel for cardiovascular stents. Biomaterials. 31:3755-3761.
Rajesh, M., P. Mukhopadhyay, G. Haskó, L. Liaudet, K. Mackie, and P. Pacher. 2010. Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells. British journal of pharmacology. 160:688-700.
Ramirez-Sanchez, I., L. Maya, G. Ceballos, and F. Villarreal. 2010. (−)-Epicatechin Activation of Endothelial Cell Endothelial Nitric Oxide Synthase, Nitric Oxide, and Related Signaling Pathways. Hypertension. 55:1398-1405.
Seif-Naraghi, S.B., M.A. Salvatore, P.J. Schup-Magoffin, D.P. Hu, and K.L. Christman. 2010. Design and characterization of an injectable pericardial matrix gel: a potentially autologous scaffold for cardiac tissue engineering. Tissue Engin. Part A. 16:2017-2027.
Villareal, F., P. Taub, A. Maisel, G. Schreiner, A. Murphy, K. Yamazaki, and G. Ceballos. 2010. Methods and compositions for treatment of ischemic conditions and conditions related to mitochondrial function. Patent Application US 20120095063 A1.
2009
Anastasiadis, P., and J.S. Allen. 2009. Ultrasound-mediated endothelial cell permeability changes with targeted contrast agents. In Ultrasonics Symposium (IUS), 2009 IEEE International. 16-18.
Csiszar, A., N. Labinskyy, R. Jimenez, J.T. Pinto, P. Ballabh, G. Losonczy, K.J. Pearson, R. de Cabo, and Z. Ungvari. 2009. Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: Role of circulating factors and SIRT1. Mechanisms of Ageing and Development. 130:518-527.
Ji, S.-R., L. Ma, C.-J. Bai, J.-M. Shi, H.-Y. Li, L.A. Potempa, J.G. Filep, J. Zhao, and Y. Wu. 2009. Monomeric C-reactive protein activates endothelial cells via interaction with lipid raft microdomains. The FASEB Journal. 23:1806-1816.
O’Neill, S.M. 2009. Insights into human neutral ceramidase transcription and the role of ceramide metabolism in the development of an inhibitor of restenosis. The Pennsylvania State University, PhD dissertation.
Singelyn, J.M., J.A. DeQuach, S.B. Seif-Naraghi, R.B. Littlefield, P.J. Schup-Magoffin, and K.L. Christman. 2009. Naturally derived myocardial matrix as an injectable scaffold for cardiac tissue engineering. Biomaterials. 30:5409-5416.
2008
Benco, J. 2008. Methods to improve the stability of celluar adhesive proteins and peptides. Patent Application US 20090018642 A1.
Csiszar, A., N. Labinskyy, H. Jo, P. Ballabh, and Z. Ungvari. 2008. Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells. Am J Phys. Heart Circ Physiol. 295:H569-577.
O’Brien, B., J. Stinson, D. Boismier, and W. Carroll. 2008. Characterization of an NbTaWZr alloy designed for magnetic resonance angiography compatible stents. Biomaterials, 29:4540-4545.
O’Neil, S., D. Olympia, T. Fox, J. Brown, T. Stover, K. Houck, R. Wilson, P. Waybill, M. Kozak, S. Levison, N. Weber, L. Karavodin, and M. Kester. 2008. C6-Ceramide-Coated Catheters Promote Re-Endothelialization of Stretch-Injured Arteries. Vasc Dis Prev, 5:200-210.
Sieveking, D., A. Buckle, D., Celermajer, and M. Ng. 2008. Strikingly Different Angiogenic Properties of Endothelial Progenitor Cell Subpopulations: Insights From a Novel Human Angiogenesis Assay. J Am Coll Cardiol, 51:660-668.
2007
Csiszar, A., N. Labinskyy, K.E. Smith, A. Rivera, E.N.T.P. Bakker, H. Jo, J. Gardner, Z. Orosz, and Z. Ungvari. 2007. Downregulation of Bone Morphogenetic Protein 4 Expression in Coronary Arterial Endothelial Cells: Role of Shear Stress and the cAMP/Protein Kinase A Pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 27:776-782.
Mukhopadhyay, P., M. Rajesh, G. Hasko, B.J. Hawkins, M. Madesh, and P. Pacher. 2007. Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy. Nat. Protocols. 2:2295-2301.
Rajesh, M., P. Mukhopadhyay, S. Bátkai, G. Haskó, L. Liaudet, J.W. Huffman, A. Csiszar, Z. Ungvari, K. Mackie, and S. Chatterjee. 2007. CB2-receptor stimulation attenuates TNF-α-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion. American journal of physiology. Heart and circulatory physiology. 293:H2210.
2006
Wildsmith, K., C. Albert, D. Anbukumar, and D. Ford. 2006. Metabolism of Myeloperoxidase-derived 2-Chlorohexadecanal. J Biol Chem, 281:16849-16860.
2004
Sharifi, B., and P. Shah. 2004. Use of pleiotrophin in the diagnosis, treatment and prevention of disease. Patent Application US 20070065409 A1.
2003
Liu, Y.-C., Y.-C. Lo, C.-W. Huang, and S.-N. Wu. 2003. Inhibitory action of ICI-182,780, an estrogen receptor antagonist, on BK Ca channel activity in cultured endothelial cells of human coronary artery. Biochemical pharmacology. 66:2053-2063.
Ng, M., S. Nakhla, A. Baoutina, W. Jessup, D. Handelsman, and D. Celermajer. 2003. Dehydroepiandrosterone, an adrenalandrogen, increases human foam cell formation. J Am Coll Cardio, 42:1967-1974.



Информация представлена исключительно в ознакомительных целях и ни при каких условиях не является публичной офертой