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Фибробласты кожи человека: HDF. Первичные клеточные линии Cell Applications.

Human Dermal Fibroblasts: HDF

HDF Фибробласты Кожи Человека (HDF) отвечают за выработку клеточного матрикса, формирующего соединительную ткань кожи, и играют важную роль при заживлении ран. HDF от Cell Applications, Inc. обеспечивают прекрасную модель для изучения многих аспектов клеточной физиологии и использовались в десятках исследовательских публикаций, особенно связанных с биологией кожи и перепрограммированием/индуцированием плюрипотентных стадий.

HDF от Cell Applications have been instrumental to

(Текст на языке оригинала)
  • Create and characterize induced pluripotent stem cells (iPSC)
  • Demonstrate the activation and efficiency of reprogramming, such as the transition of fibroblasts into platelets, or mesenchymal stromal cells into iPSC
  • Identify markers that distinguish chondrocytes and synovial cells
  • Establish protocols for tissue engineering, biomaterials, and synthetic collagens.
  • Examine molecular gene regulation & activation, epigenetic modifications, histone ubiquitination and miRNA expression.
  • Describe cell physiology and behavior, includinig cell adhesion, integrins, cartilage link protein and elastic fiber formation. Others rely on the cells to characterize mitochondrial metabolism, angiogenesis and tissue remodeling.
  • Provide insights into disease and pathology: UVA effects, stress-induced premature senescence, skin aging, elasticity and dermal integrity, as well as tumor cell pluripotency markers.
  • Develop potential clinical treatments and therapeutics: Cell survival factors and natural antioxidants like astaxanthin. Some investigators have observed approaches that promote wound healing, or protect skin from UVA-induced photo-aging.

HDF Total Kit: Media, Subculture Reagents & Cells, Adult 106K-05a 43157.5 руб. 1 Kit
HDF Total Kit: Media, Subculture Reagents & Cells, Fetal 106K-05f 67530.21 руб. 1 Kit
HDF Total Kit: Media, Subculture Reagents & Cells, Neonatal 106K-05n 56830.31 руб. 1 Kit

Cryopreserved HDF 106-05a 27344.97 руб. 1 Ampoule

Cryopreserved HDF 106-05f 51717.68 руб. 1 Ampoule

Cryopreserved HDF 106-05n 41017.78 руб. 1 Ampoule

Proliferating HDF 107-96Wa 64201.33 руб. 96 well
Proliferating HDF 107-6Wa 49934.58 руб. 6 well
Proliferating HDF 107-25a 27344.97 руб. T-25 Flask
Proliferating HDF 107-75a 49934.58 руб. T-75 Flask

Proliferating HDF 107-6Wf 72523.54 руб. 6 well
Proliferating HDF 107-96Wf 86790.93 руб. 96 well
Proliferating HDF 107-25f 51717.68 руб. T-25 Flask
Proliferating HDF 107-75f 74307.29 руб. T-75 Flask

Proliferating HDF 107-25n 41017.78 руб. T-25 Flask
Proliferating HDF 107-75n 63606.74 руб. T-75 Flask
Proliferating HDF 107-96Wn 77874.14 руб. 96 well
Proliferating HDF 107-6Wn 63606.74 руб. 6 well

Extended Family Products

100 tests 028-S 3963.02 руб. Sample
500 tests 028-01 15337.25 руб. 1 bottle

25 x 24-Well Rxns TF103KS 5938.7 руб. 1 Sample Kit
250 x 24-Well Rxns TF103K 44583.98 руб. 1 Kit

Human Fibroblast Growth Factor acidic RP1029-10 8916.8 руб. 10 ug
Human Fibroblast Growth Factor acidic RP1029-1000 172392.7 руб. 1000 ug
Human Fibroblast Growth Factor acidic RP1029-50 21400.44 руб. 50 ug

Human FGF9 ELISA Kit CL0348 50528.52 руб. 96 wells

Total RNA prepared from Human Dermal Fibroblasts, adult 106-R10a 38639.45 руб. 10 ug
Total RNA prepared from Human Dermal Fibroblasts, adult 106-R25a 77279.55 руб. 25 ug
Total RNA prepared from Human Dermal Fibroblasts, fetal 106-R10f 49934.58 руб. 10 ug
Total RNA prepared from Human Dermal Fibroblasts, fetal 106-R25f 99868.51 руб. 25 ug
Total RNA prepared from Human Dermal Fibroblasts, neonatal 106-R10n 38639.45 руб. 10 ug
Total RNA prepared from Human Dermal Fibroblasts, neonatal 106-R25n 77279.55 руб. 25 ug

100 ml each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution 090K 6063.19 руб. 100 ml

Related Products

Basal medium (contains no growth supplement).В  Add GS before use. 115-500 6301.15 руб. 500 ml

All-in-one ready-to-use 116-500 10937.86 руб. 500 ml

Basal medium & growth supplement sold together packaged separately 116K-500 13078.23 руб. Yields 500 ml

Added to Basal Medium to create Growth Medium 116-GS 5587.91 руб. 15 ml


Normal human neonatal foreskin or adult skin. Each lot is tested negative for HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi.
Cryopreserved ampoule:
Primary culture, >500,000 cells in Fibroblast Basal Medium containing 10% FBS & 10% DMSO.
Kit contains:
Ampoule of cryopreserved HDF (106-05), 500 ml Growth Medium (116-500), and a Subculture Reagent Kit (090K).
Proliferating Cells:
Shipped in Growth Medium at 1st passage in either flasks or multiwell dishes.
Population doublings:
Can be cultured at least 16 doublings



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